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Food for thought: when excess safety precautions clash with reality on the ground (Ebola outbreak, see News tab)
05 September 2018
The Challenges of Poliovirus Eradication, by J.Yelle
12 January 2017Following the successful efforts to wipe out the virus of Smallpox (Variola virus) that started in the 1950s and officially realized their goal in 19803, the World Health Organization (WHO) made a commitment in 1988 to eradicate Poliovirus and poliomyelitis and achieve a Polio-free world by 2000. This ambitious project proved to be much more challenging than initially anticipated.
See complete publication in "NEWS" section (Tab)
The Urgent Need for Broad-Spectrum Antiviral Drugs, by J. Yelle
18 March 2015
Conferences
Simplified taxonomy of main viruses infecting humans
The diagram below displays a simplified classification scheme of the main viruses commonly associated with human diseases, based on International Committee on Taxonomy of Viruses Database (ICTVdB) and other sources.
Viral family names end with "viridae", sub-family with "virinae" and genus with "virus". Mononegavirales and Nidovirales represent two viral orders regrouping viral families.
In the diagram, viruses with single-stranded DNA genome are indicated as ss DNA and those with single-stranded RNA, as ss RNA. Viruses with double-stranded DNA genome are indicated as ds DNA and those with double-stranded RNA, as ds RNA.
Please note that some of the viruses listed below are naturally found in animal species but can occasionally infect humans as well (zoonoses).
Use the diagram to facilitate your search in the database and identify viruses according to their taxonomic status.
- Reoviridae (ds RNA)
- Orthoreovirus: Mammalian orthoreovirus
Rotavirus: Human Rotavirus - Hepadnaviridae (DNA - RNA - DNA)
- Adenoviridae (ds DNA)
- Mastadenovirus: Human adenoviruses
- Poxviridae (ds DNA)
- Orthopoxvirus: Vaccinia virus; Variola virus
- Herpesviridae (ds DNA)
- Alphaherpesvirinae
Simplexvirus: Human herpesvirus 1, 2 (Herpes simplex, HSV-1, HSV-2)
Varicellovirus: Human herpesvirus 3 (Varicella-Zoster virus, VZV)
Betaherpesvirinae
Cytomegalovirus: Human herpesvirus 5 (Human cytomegalovirus, CMV)
Roseolovirus: Human herpesvirus 6, 7
Gammaherpesvirinae
Lymphocryptovirus: Human herpesvirus 4 (Epstein-Barr virus, EBV)
Rhadinovirus: Human herpesvirus 8 (Kaposis sarcoma-associated herpesvirus, KSHV) - Papillomaviridae (ds DNA)
- Alphapapillomavirus: Human papillomavirus 2, 6, 7, 10, 16, 18, 26, 32, 34, 53, 54, 61, 71, cand90
Betapapillomavirus: Human papillomavirus 5, 9, 49, cand92, cand96
Gammapapillomavirus: Human papillomavirus 4, 48, 50, 60, 88
Mupapillomavirus: Human papillomavirus 1, 63
Nupapillomavirus: Human papillomavirus 41 - Polymaviridae (ds DNA)
- Polyomavirus (SV40-like subgroup): BK polyomavirus (BKPyV); JC polyomavirus(JCPyV); KI polyomavirus (Karolinska Institutet virus, KIPyV); WU polyomavirus (Washington University virus, WUPyV)
Polyomavirus (Murine polyomavirus-like subgroup): Merkel cell polyomavirus (MCV or MCPyV) - Parvoviridae (ss DNA)
- Erythrovirus: Human parvovirus B19
Dependovirus: Human adeno-associated virus
Bocavirus: Human bocavirus (HBoV) - Hepatitis delta virus (HDV) (ss RNA (-) polarity)
- NOT ASSIGNED TO A FAMILY
- Rhabdoviridae (Mononegavirales) (ss RNA (-) polarity)
- Lyssavirus: Rabies virus
Vesiculovirus: Vesicular Stomatitis virus (VSV) - Filoviridae (Mononegavirales) (ss RNA (-) polarity)
- Marburgvirus: Lake Victoria Marburgvirus (Marburg virus)
Ebolavirus: Zaire virus (Ebola virus) - Paramyxoviridae (Mononegavirales) (ss RNA (-) polarity)
- Respirovirus: Human parainfluenzavirus 1, 3 (PIV)
Morbillivirus: Measles virus
Rubulavirus: Mumps virus Human parainfluenzavirus 2, 4 (PIV)
Henipavirus: Hendra virus; Nipah virus
Pneumovirus: Human respiratory syncytial virus (RSV)
Metapneumovirus: Human metapneumovirus (MPV) - Bunyaviridae (ss RNA (-) polarity)
- Orthobunyavirus: Bunyamwera virus; California Encephalitis virus
Hantavirus: Hantaan virus; Sin Nombre virus
Nairovirus: Crimean-Congo Haemorrhagic Fever virus (CCHFV)
Phlebovirus: Rift Valley Fever virus (RVFV); Punta Toro virus - Arenaviridae (ss RNA (-) polarity)
- Orthomyxoviridae (ss RNA (-) polarity)
- Influenzavirus A: Influenza A virus
Influenzavirus B: Influenza B virus
Influenzavirus C: Influenza C virus - Coronaviridae (Nidovirales) (ss RNA (+) polarity)
- Flaviviridae (ss RNA (+) polarity)
- Flavivirus: Yellow Fever virus (YFV); Tick-borne Encephalitis virus (TBEV); Dengue virus; Modoc virus; Japanese Encephalitis virus (JEV); St-Louis Encephalitis virus (SLEV); West Nile virus (WNV)
Hepacivirus: Hepatitis C virus (HCV); Hepatitis G virus (HGV, GB virus) - Togaviridae (ss RNA (+) polarity)
- Alphavirus: Sindbis virus; Eastern Equine Encephalitis virus (EEE); Semliki Forest virus; Venezuelan Equine Encephalitis virus (VEE); Western Equine Encephalitis virus (WEE); Chikungunya virus
Rubivirus: Rubella virus - Picornaviridae (ss RNA (+) polarity)
- Hepatitis E Virus (HEV) (ss RNA (+) polarity)
- NOT ASSIGNED TO A FAMILY
- Caliciviridae (ss RNA (+) polarity)
- Norovirus: Norwalk virus
Sapovirus: Sapporo virus - Astroviridae (ss RNA (+) polarity)
- Mamastroviridae: Human astrovirus 1 to 8
- Retroviridae (RNA - DNA - RNA)
- Deltaretrovirus: Human T-lymphotropic virus 1, 2 (HTLV-1, 2)
Gammaretrovirus: Xenotropic murine leukemia-related virus (XMRV)
Lentivirus: Human immunodeficiency virus 1, 2 (HIV-1, 2)